CENPU Human
目录号 : GP23126Centromere Protein-U Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 80.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Centromere Protein U; MLF1IP; Polo-Box-InteractingProtein 1; MLF1 Interacting Protein; Centromere Protein Of 50 KDa; InterphaseCentromere Complex Protein 24; KLIP1; PBIP1; KSHV Latent NuclearAntigen-Interacting Protein 1; MLF1-Interacting Protein; CENP50; CENPU50; KSHVLatent Nuclear Antigen Interacting Protein 1; CENP-50; CENP-U; ICEN24. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSTRRKVKS AEKISTQRHE VIRTTASSEL SEKPAESVTS KKTGPLSAQPSVEKENLAIE SQSKTQKKGK ISHDKRKKSR SKAIGSDTSD IVHIWCPEGM KTSDIKELNI VLPEFEKTHLEHQQRIESKV CKAAIATFYV NVKEQFIKML KESQMLTNLK RKNAKMISDI EKKRQRMIEV QDELLRLEPQ LKQLQTKYDE LKERKSSLRNAAYFLSNLKQ LYQDYSDVQA QEPNVKETYD SSSLPALLFK ARTLLGAESH LRNINHQLEK LLDQG | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | CENPU protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and0.4M Urea. | ||
Centromere Protein U, also known as CENPU is aspecialized chromatin domain, present throughout the cell cycle. CENPU performsas a platform on which the transient assembly of the kinetochore takes place duringmitosis. CENPU plays a major role in the correct PLK1 localization to themitotic kinetochores. A scaffold protein is responsible for the first recruitmentand maintenance of the kinetochore PLK1 population until its degradation. CENPUis also implicated in transcriptional repression.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.