CHRNA3 Human
目录号 : GP23157Cholinergic Receptor Nicotinic Alpha 3 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 80.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Cholinergic Receptor; Nicotinic; Alpha 3 (Neuronal);Cholinergic Receptor; Nicotinic; Alpha Polypeptide 3; NACHRA3; LNCR2; PAOD2;Neuronal Nicotinic Acetylcholine Receptor; Alpha3 Subunit; NeuronalAcetylcholine Receptor Subunit Alpha-3; Acetylcholine Receptor; Alpha 3(Neuronal); Nicotinic; Neuronal acetylcholine receptor subunit alpha-3. | ||
Amino Acid Sequence | MGSSHHHHHHSSGLVPRGSH MGSSEAEHRLFERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEFMRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFGSWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | CHRNA3 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH8.0) and 10% glycerol. |
Cholinergic Receptor Nicotinic Alpha 3, also known as CHRNA3 is part ofthe nicotinic acetylcholine receptor family. Proteins of this family formpentameric complexes comprised of both alpha & beta subunits. Furthermore,CHRNA3 is ligand-gated ions channel which prticipates in neurotransmission.CHRNA3 has been associated with an increased risk of smoking initiation as wellas an increased susceptibility to lung cancer.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.