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CHRNA3 Human

目录号 : GP23157

Cholinergic Receptor Nicotinic Alpha 3 Human Recombinant

CHRNA3 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

CHRNA3 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 232 amino acids (32-240 a.a) andhaving a molecular mass of 27kDa.CHRNA3 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 80.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Cholinergic Receptor; Nicotinic; Alpha 3 (Neuronal);Cholinergic Receptor; Nicotinic; Alpha Polypeptide 3; NACHRA3; LNCR2; PAOD2;Neuronal Nicotinic Acetylcholine Receptor; Alpha3 Subunit; NeuronalAcetylcholine Receptor Subunit Alpha-3; Acetylcholine Receptor; Alpha 3(Neuronal); Nicotinic; Neuronal acetylcholine receptor subunit alpha-3.
Amino Acid Sequence MGSSHHHHHHSSGLVPRGSH MGSSEAEHRLFERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEFMRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFGSWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CHRNA3 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH8.0) and 10% glycerol.

Introduction

Cholinergic Receptor Nicotinic Alpha 3, also known as CHRNA3 is part ofthe nicotinic acetylcholine receptor family. Proteins of this family formpentameric complexes comprised of both alpha & beta subunits. Furthermore,CHRNA3 is ligand-gated ions channel which prticipates in neurotransmission.CHRNA3 has been associated with an increased risk of smoking initiation as wellas an increased susceptibility to lung cancer.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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