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CKMT3 Human

目录号 : GP22465

Creatine Kinase Muscle Type-3 Human Recombinant

CKMT3 Human Chemical Structure

规格 价格 库存 购买数量
10μg
¥840.00
5-10工作日
50μg
¥2,030.00
5-10工作日
1mg
¥13,230.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

CKMT3 Human Recombinant produced in Pichia Pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MM Isoenzyme in ELISA.The CKMT3 is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. Source Pichia Pastoris.
Phycical Appearance Sterile Filtered colorless liquid formulation. Shipping Condition Shipped with Ice Packs.
Synonyms Creatine kinase M-type; EC 2.7.3.2; Creatine kinase M chain; M-CK; CKM; CKMM; CKMMITIII.
Stability CKMT3 although stable at 15°C for 7 days, should be stored below -18°C . Please prevent freeze-thaw cycles.
Biological Activity The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 ?mole creatine phosphate was 500 IU/mg at 37 degrees celsius corresponding to a Specific Activity of 2,000ng/ml.
Formulation Each mg of protein contains 20mM Tris pH-8, 1mM EDTA and 1mM DTT.

Introduction

The three isoenzymes (MM, MB, and BB) are found in muscle, cardiac and brain tissues. These recombinant proteins are ideal for calibrating diagnostic instruments and researching neuromuscular diseases. Creatine Kinases can be used for indications in many neuromuscular applications. These disorders include cardiac disease, mitochondrial disorders, inflammatory myopathies, myasthenia, polymyositis, McArdle's disease, NMJ disorders, muscular dystrophy, ALS, hypo and hyperthyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and other that create elevated or reduced levels of Creatine Kinases.

Biological Activity

The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 ?mole creatine phosphate was 500 IU/mg at 37 degrees celsius corresponding to a Specific Activity of 2,000ng/ml.

Stability

CKMT3 although stable at 15°C for 7 days, should be stored below -18°C . Please prevent freeze-thaw cycles.

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