CoV-2-S1 (319-541)
目录号 : GP26393The HEK293 derived recombinant protein contains the Coronavirus 2019 Spike Glycoprotein S1 Receptor Binding Domain [ RBD ], Wuhan-Hu-1 strain, amino acids 319-541 fused toHis tag at C-terminal
Sample solution is provided at 25 µL, 10mM.
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The HEK293 derived recombinant protein contains the Coronavirus 2019 Spike Glycoprotein S1 Receptor Binding Domain [ RBD ], Wuhan-Hu-1 strain, amino acids 319-541 fused toHis tag at C-terminal.
| Purity | Protein is >90% pure as determined SDS-PAGE. | Source | HEK293Cells. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | withIcePacks |
| Stability | CoV-2 S1RBD Protein is shipped on ice packs. Upon arrival, Store at -20°C. | ||
| Biological Activity | SARS CoV-2 Spike Glycoprotein S1 RBD was tested for its biological functionality by its binding to recombinant ACE2 receptor protein confirmed by structural complementation reporter assay (NanoBiT®). | ||
| Formulation | CoV-S1 RBDproteinis 1mg/ml contains 20mM sodium phosphate (NaPP), 300mM NaCl, pH7.2 | ||
A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
SARS CoV-2 Spike Glycoprotein S1 RBD was tested for its biological functionality by its binding to recombinant ACE2 receptor protein confirmed by structural complementation reporter assay (NanoBiT®).
Purified by Metal-Afinitychromatographic technique.
CoV-2 S1RBD Protein is shipped on ice packs. Upon arrival, Store at -20°C.