CTLA4 Human, Sf9
目录号 : GP20155Cytotoxic T-Lymphocyte Associated Antigen-4 Human Recombinant, Sf9
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | CytotoxicT-Lymphocyte Associated Protein 4; Cytotoxic T-Lymphocyte-Associated Protein 4;Insulin-Dependent Diabetes Mellitus 12; Celiac Disease 3; CTLA-4; CD152; LigandAnd Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4; CytotoxicT Lymphocyte Associated Antigen 4 Short Spliced Form; CytotoxicT-Lymphocyte-Associated Serine Esterase-4; Cytotoxic T-Lymphocyte-AssociatedAntigen 4; CD152 Isoform; CD152 Antigen; CELIAC3; IDDM12; ALPS5; GRD4; GSE; CD;Cytotoxic T-lymphocyte protein 4; CTLA4. | ||
| Amino Acid Sequence | ADLKAMHVAQPAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQVNLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSDH HHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | CTLA4 protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 20% glycerol. | ||
CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.