CTSL Human
目录号 : GP21507Cathepsin-L Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Cathepsin L; CTSL1; Cathepsin L1; Major Excreted Protein;MEP; EC 3.4.22.15; CATL; EC 3.4.22. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSTLTFDHS LEAQWTKWKA MHNRLYGMNE EGWRRAVWEK NMKMIELHNQ EYREGKHSFT MAMNAFGDMT SEEFRQVMNG FQNRKPRKGK VFQEPLFYEA PRSVDWREKG YVTPVKNQGQ CGSCWAFSAT GALEGQMFRK TGRLISLSEQ NLVDCSGPQG NEGCNGGLMD YAFQYVQDNG GLDSEESYPY EATEESCKYN PKYSVANDTG FVDIPKQEKA LMKAVATVGP ISVAIDAGHE SFLFYKEGIY FEPDCSSEDM DHGVLVVGYG FESTESDNNK YWLVKNSWGE EWGMGGYVKM AKDRRNHCGI ASAASYPTV. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | CTSL protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.0) and10% glycerol. | ||
Cathepsin-L also known as CTSL is a member of the peptidase C1 family.CTSL, is a dimer composed of disulfide-linked heavy and light chains, bothformed from a single protein precursor. Furthermore, CTSL is a lysosomalcysteine proteinase which takes a main part in intracellular proteincatabolism. CTSL substrates include collagen and elastin, as well as alpha-1protease inhibitor, which is the most important controlling element ofneutrophil elastase activity. CTSL has been implicated in a number of pathologicprocesses, including myofibril necrosis in myopathies and in myocardialischemia, and in the renal tubular response to proteinuria. Multiplealternatively spliced transcript variants have been found for CTSL.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.