CuprosGreen

Although copper exists only in trace amounts in living organisms, as a transition metal, it plays an important role in the active centers of enzymes that regulate life phenomena such as respiration and metabolism. Specifically, copper promotes the synthesis of hemoglobin by helping to transport iron, thereby activating iron metabolism; at the same time, it binds to superoxide dismutase1 (SOD1) to remove reactive oxygen species. This shows that copper plays an important role in maintaining our life activities.

In addition, copper has also attracted attention in recent years in the study of cell death. Ferroptosis, a relatively new cell death pathway that starts with iron (II) ions, is very actively studied. Unlike Ferroptosis, a new cell death pathway (Cuproptosis) that starts with copper (I) ions has also been discovered. CuprosGreen is a fluorescent probe that selectively reacts with copper (I) ions in cells and emits fluorescence. Because it is cell membrane permeable, it can perform live cell imaging of copper (I) ions.

Features:

● A reagent that can selectively detect monovalent copper ions in cells.
● Suitable for microscopic observation and microplate reader reading detection.
● Easy-to-use solution type, no additional dissolving operation required.

尽管铜在生物体内仅以微量存在，但作为一种过渡金属，它在调控呼吸和代谢等生命现象的酶的活性中心中起到了重要作用。具体来说，铜通过帮助运输铁来促进血红蛋白的合成，从而活跃铁代谢；同时，它与superoxide dismutase1 (SOD1)结合，以清除活性氧。这表明铜在维持我们的生命活动中具有重要作用。

此外，在关于细胞死亡的研究中，近年来铜也引起了关注。作为一种相对较新的细胞死亡途径，以铁(II)离子为起点的Ferroptosis研究非常活跃。而与Ferroptosis不同的是，以铜(I)离子为起点的新型细胞死亡途径（Cuproptosis）也被发现了。CuprosGreen是一种能选择性地与细胞内的铜(I)离子反应并发出荧光的荧光探针。由于它具有细胞膜透过性，因此能够进行铜(I)离子的活细胞成像。

特点：

● 能够选择性检测细胞内一价铜离子的试剂。
● 适用于显微镜观察和酶标仪读数检测。
● 易于使用的溶液类型，无需额外的溶解操作。