Cyclohexyl fentanyl-d5 (hydrochloride) (exempt preparation)
目录号 : GC91606Cyclohexyl fentanyl-d5 (hydrochloride) (exempt preparation) is intended for use as an internal standard for the quantification of cyclohexyl fentanyl by GC- or LC-MS.
Cas No.:2747915-25-7
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Cyclohexyl fentanyl-d5 (hydrochloride) (exempt preparation) is intended for use as an internal standard for the quantification of cyclohexyl fentanyl by GC- or LC-MS. Cyclohexyl fentanyl is categorized as an opioid.[1],[2] Cyclohexyl fentanyl-d5 is regulated as a Schedule I compound in the United States. Cyclohexyl fentanyl-d5 (hydrochloride) (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
References:
[1].Åstrand, A., Vikingsson, S., Jakobsen, I., et al.Activation of the μ-opioid receptor by alicyclic fentanyls: Changes from high potency full agonists to low potency partial agonists with increasing alicyclic substructureDrug Test Anal.13(1)169-174(2020).
[2].Eshleman, A.J., Nagarajan, S., Wolfrum, K.M., et al.Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptorsBiochem. Pharmacol.182114293(2020).
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.3143 mL | 11.5714 mL | 23.1428 mL |
| 5 mM | 0.4629 mL | 2.3143 mL | 4.6286 mL |
| 10 mM | 0.2314 mL | 1.1571 mL | 2.3143 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。