Cyclophilin F Rat Bioactive
目录号 : GP21531Cyclophilin-F Rat Recombinant Bioactive
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Peptidyl-prolyl cis-trans isomerase F; mitochondrial; PPIaseF; Cyclophilin D; CyP-D; CypD; Cyclophilin F; Rotamase F. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSCSDGGAR GANSSSQNPL VYLDVGADGQ PLGRVVLELK ADVVPKTAENFRALCTGEKG FGYKGSTFHR VIPAFMCQAG DFTNHNGTGG KSIYGSRFPD ENFTLKHVGP GVLSMANAGPNTNGSQFFIC TIKTDWLDGK HVVFGHVKEG MDVVKKIESFGSKSGKTSKK IVITDCGQLS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Biological Activity | Specificactivity is > 1,300 nmol/min/mg, and is defined as the amount of enzyme thatcleaves 1nmol of suc-AAFP-PNA per minute at 37C in TrisиCHCl pH 8.0 using chymotrypsin. | ||
| Formulation | CyclophilinF protein solution (1mg/ml) containing Phosphate Buffered Saline (pH 7.4), 10%glycerol and 1mM DTT. | ||
PPIF is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIF accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIF is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Specificactivity is > 1,300 nmol/min/mg, and is defined as the amount of enzyme thatcleaves 1nmol of suc-AAFP-PNA per minute at 37C in TrisиCHCl pH 8.0 using chymotrypsin.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.