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Deslorelin

目录号 : GP21238

Deslorelin

Deslorelin Chemical Structure

规格 价格 库存 购买数量
5mg
¥840.00
5-10工作日
25mg
¥2,800.00
5-10工作日
100mg
¥8,400.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

Deslorelin is a potent LHRH/GnRH agonist has a molecular formula of C64H83N17O12,pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHC2H5having an Mw of 1281.64 Dalton.

Product Data

Purity Greater than 99.0% as determined byRP-HPLC. Source
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Solubility It is recommended to reconstitute the lyophilized Deslorelin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized Deslorelin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Deslorelin should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation The Deslorelin peptide was lyophilized with no additives.

Introduction

Deslorelin is being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or testicles. It belongs to the family of drugs called gonadotropin-releasing hormone analogs. It is used for the induction of ovulation in mares. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production.

Stability

Lyophilized Deslorelin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Deslorelin should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

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