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Diquat-d4 (bromide) Sale

目录号 : GC47240

A neuropeptide with diverse biological activities

Diquat-d4 (bromide) Chemical Structure

规格 价格 库存 购买数量
1 mg
¥839.00
现货
5 mg
¥3,358.00
现货
10 mg
¥6,304.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Diquat-d4 is intended for use as an internal standard for the quantification of diquat by GC- or LC-MS. Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1 Diquat administration has been used to induce oxidative stress in vitro and in animal models.2,3,4 It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2 Formulations containing diquat have been used in agriculture for crop desiccation and defoliation.

1.Moreland, D.E.Mechanisms of action of herbicidesAnn. Rev. Plant Physiol.31597-638(1980) 2.Cao, S., Wu, H., Wang, C., et al.Diquat-induced oxidative stress increases intestinal permeability, impairs mitochondrial function, and triggers mitophagy in pigletsJ. Anim. Sci.96(5)1795-1805(2018) 3.Singh, P., Hanson, P.S., and Morris, C.M.Sirtuin-2 protects neural cells from oxidative stress and is elevated in neurodegenerationParkinsons Dis.2017:2643587(2017) 4.TomÁšek, O., GabrielovÁ, B., Ka?er, P., et al.Opposing effects of oxidative challenge and carotenoids on antioxidant status and condition-dependent sexual signallingSci. Rep.6:23546(2016)

Chemical Properties

Cas No. N/A SDF
Canonical SMILES [2H]C1([2H])[N+]2=CC=CC=C2C3=[N+](C=CC=C3)C1([2H])[2H].[Br-].[Br-]
分子式 C12H8D4N2.2Br 分子量 348.1
溶解度 DMSO: slightly soluble,Methanol: slightly soluble,Water: slightly soluble 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 2.8727 mL 14.3637 mL 28.7274 mL
5 mM 0.5745 mL 2.8727 mL 5.7455 mL
10 mM 0.2873 mL 1.4364 mL 2.8727 mL
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