Dodecanoyl D-Sucrose
(Synonyms: 蔗糖十二烷酸酯) 目录号 : GC47257A nonionic surfactant
Cas No.:25339-99-5
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >97.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Dodecanoyl D-sucrose is a nonionic surfactant.1 It is active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay when used at a concentration of 255 mM. Transcutaneous immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to immunization with uncoated ovalbumin.2 Topical administration of a dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel.3 Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions.4
1.Zhao, L., Zhang, H., Hao, T., et al.In vitro antibacterial activities and mechanism of sugar fatty acid esters against five food-related bacteriaFood Chem.187370-377(2015) 2.Kitaoka, M., Imamura, K., Hirakawa, Y., et al.Sucrose laurate-enhanced transcutaneous immunization with a solid-in-oil nanodispersionMedChemComm.5(1)20-24(2014) 3.Vermeire, A., De Muynck, C., Vandenbossche, G., et al.Sucrose laurate gels as a percutaneous delivery system for oestradiol in rabbitsJ. Pharm. Pharmacol.48(5)463-467(1996) 4.Zhang, X., Wei, W., Cao, X., et al.Characterization of enzymatically prepared sugar medium-chain fatty acid monoestersJ. Sci. Food Agric.95(8)1631-1637(2015)
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 1.9062 mL | 9.5311 mL | 19.0621 mL |
| 5 mM | 0.3812 mL | 1.9062 mL | 3.8124 mL |
| 10 mM | 0.1906 mL | 0.9531 mL | 1.9062 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。