DOK4 Human
目录号 : GP23332Docking Protein 4 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | docking protein 4; Downstream of tyrosine kinase 4; IRS-5; IRS5. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMATNFSD IVKQGYVKMK SRKLGIYRRC WLVFRKSSSK GPQRLEKYPDEKSVCLRGCP KVTEISNVKC VTRLPKETKR QAVAIIFTDD SARTFTCDSE LEAEEWYKTL SVECLGSRLNDISLGEPDLL APGVQCEQTD RFNVFLLPCP NLDVYGECKL QITHENIYLW DIHNPRVKLV SWPLCSLRRY GRDATRFTFE AGRMCDAGEGLYTFQTQEGE QIYQRVHSAT LAIAEQHKRV LLEMEKNVRL LNKGTEHYSY PCTPTTMLPR SAYWHHITGSQNIAEASSYA GEGYGAAQAS SETDLLNRFI LLKPKPSQGD SSEAKTPSQ. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | DOK4 protein solution (1mg/ml) contains 20mM Tris-HClbuffer (pH 8.0), 0.4M UREA and 10% glycerol. | ||
Docking Protein 4(DOK4) is amember of the DOK family. DOK proteins are enzymatically inert adaptor orscaffolding proteins. The DOK proteins present a docking platform for the compilationof multimolecular signaling complexes. DOK4 serves in RET-mediated neuriteoutgrowth and has a positive role in activation of the MAP kinase pathway. DOK4is a putative link with downstream effectors of RET in neuronaldifferentiation. DOK4 is involved in the regulation of the immune responseinduced by T-cells.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.