DPP4 Protein
目录号 : GP21570Human Dipeptidyl Peptidase-IV
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95% as determined by SDS-PAGE. | Source | Human Placenta. |
| Phycical Appearance | Filtered lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | DPP-IV; DPPIV; DPP4; DPP-4; Dipeptidyl Peptidase-IV; Dipeptidyl Peptidase-4; CD26; adenosine deaminase complexing protein 2; Dipeptidylpeptidase-IV; CD-26; ADABP; ADCP2; DPIV; TP103; DP-IV; DP-4; DP4. | ||
| Solubility | Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. | ||
| Stability | Store lyophilized protein at -20°C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C . | ||
| Biological Activity | One unit is defined as the amount of enzyme which will hydrolyze 1ж╠m of H-Gly-Pro-pNA per 1min at 25°C , pH 7.8. | ||
| Formulation | Each 70ng were lyophilized from 29.1µl containing 2mM Tris-HCl, pH 8.0. | ||
Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense.
One unit is defined as the amount of enzyme which will hydrolyze 1ж╠m of H-Gly-Pro-pNA per 1min at 25°C , pH 7.8.
Store lyophilized protein at -20°C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C .