DPPD-Q
(Synonyms: C.I. 56000,2,5-Dianilino-1,4-benzoquinone,2,5-Dianilino-p-benzoquinone,2,5-Dianilino-para-benzoquinone,N,N′-Diphenyl-1,4-phenylenediamine quinone,N,N′-Diphenyl-p-phenylenediamine quinone,N,N′-Diphenyl-para-phenylenediamine quinone,NSC 11) 目录号 : GC91483DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD.
Cas No.: 3421-08-7
Sample solution is provided at 25 µL, 10mM.
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DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD.1,2,3 It inhibits jack bean urease by 91.4% when used at a concentration of 5 µM.[4] DPPD-Q is less toxic to the aquatic bacterium V. fischeri than DPPD (EC50 = 1.76 mg/ml).[5] It has been found in tire wear particles and crumb rubber, particulate matter 2.5 (PM2.5), and wastewater influent and effluent.1,2,3
References:
[1].Zhao, H.N., Hu, X., Gonzalez, M., et al.Screening p-phenylenediamine antioxidants, their transformation products, and industrial chemical additives in crumb rubber and elastomeric consumer productsEnviron. Sci. Technol.57(7)2779-2791(2023).
[2].Wang, W., Cao, G., Zhang, J., et al.Beyond substituted p-phenylenediamine antioxidants: Prevalence of their quinone derivatives in PM[2].5Environ. Sci. Technol.56(15)10629-10637(2022).
[3].Cao, G., Wang, W., Zhang, J., et al.Occurrence and fate of substituted p-phenylenediamine-derived quinones in Hong Kong wastewater treatment plantsEnviron. Sci. Technol.57(41)15635-15643(2023).
[4].Nain-Perez, A., Barbosa, L.C.A., Rodríguez-Hernández, D., et al.Antiureolytic activity of substituted 2,5-diaminobenzoquinonesChem. Biodivers.16(12)e1900503(2019).
[5].Wang, W., Chen, Y., Fang, J., et al.Toxicity of substituted p-phenylenediamine antioxidants and their derived novel quinones on aquatic bacterium: Acute effects and mechanistic insightsJ. Hazard. Mater.469:133900(2024).
| Cas No. | 3421-08-7 | SDF | Download SDF |
| 别名 | C.I. 56000,2,5-Dianilino-1,4-benzoquinone,2,5-Dianilino-p-benzoquinone,2,5-Dianilino-para-benzoquinone,N,N′-Diphenyl-1,4-phenylenediamine quinone,N,N′-Diphenyl-p-phenylenediamine quinone,N,N′-Diphenyl-para-phenylenediamine quinone,NSC 11 | ||
| 分子式 | C18H14N2O2 | 分子量 | 290.3 |
| 溶解度 | Trifluoroacetic acid: Soluble | 储存条件 | -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.4447 mL | 17.2236 mL | 34.4471 mL |
| 5 mM | 0.6889 mL | 3.4447 mL | 6.8894 mL |
| 10 mM | 0.3445 mL | 1.7224 mL | 3.4447 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet