DYNLL1 Human
目录号 : GP23343Dynein Light Chain LC8 Type-1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
DYNLL1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 109 amino acids (1-89a.a.) and having a molecular mass of 12.5kDa. The DYNLL1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | PIN; DLC1; DLC8; DNCL1; DNCLC1; Dynein Light Chain LC8-type 1; Dynein Cytoplasmic Light polypeptide 1; Protein Inhibitor of Neuronal Nitric Oxide Synthase | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles. | ||
Formulation | The DYNLL1 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 0.2M NaCl, 1mM DTT and 10% glycerol. |
DYNLL1 is a protein that cooperates with NOS1 causing NOS1 inhibition. Binding of DYNLL1 weakens NOS1 (Neuronal nitric oxide synthase) dimer, a conformation needed for activity, and it regulates several biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that demonstrates high expression in testis and moderate expression in brain.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.