EBI3 Mouse
目录号 : GP20164Epstein Barr Virus Induced 3 Mouse Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | IL-27B; IL27B; IL 27-B; EBI-3; Interleukin-27 beta; IL-27 subunit beta; Epstein-Barr virus-induced gene 3 protein homolog; EBI3. | ||
Amino Acid Sequence | MALVALSQPR VQCHASRYPV AVDCSWTPLQ APNSTRSTSF IATYRLGVAT QQQSQPCLQR SPQASRCTIP DVHLFSTVPY MLNVTAVHPG GASSSLLAFV AERIIKPDPP EGVRLRTAGQ RLQVLWHPPA SWPFPDIFSL KYRLRYRRRG ASHFRQVGPI EATTFTLRNS KPHAKYCIQV SAQDLTDYGK PSDWSLPGQV ESAPHKP. | ||
Solubility | It is recommended to reconstitute the lyophilized EBI3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
Stability | Lyophilized EBI3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution EBI3 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
Formulation | EBI3 was lyophilized from 10mM Sodium Citrate pH-3. |
EBI3 has an induced expression in B lymphocytes in reaction to Epstein-Barr virus infection. EBI3 encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form iIL-27. EBI3 drives rapid clonal expansion of naive cd4(+) t-cells. EBI3 strongly synergizes with IL-12 to activate IFN-gamma production of naive cd4(+) t-cells. EBI3 mediates its biologic effects through the cytokine receptor wsx-1/tccr.
Lyophilized EBI3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution EBI3 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.