EDAR Human
目录号 : GP23351Ectodysplasin A Receptor Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Ectodysplasin A Receptor; DL; Ectodysplasin 1; AnhidroticReceptor; Anhidrotic Ectodysplasin Receptor 1; Ectodermal Dysplasia Receptor;Ectodysplasin-A Receptor; Downless Homolog; EDA-A1 Receptor; ECTD10A; ECTD10B; EDA3;HRM1; ED3; Tumor Necrosis Factor Receptor Superfamily Member EDAR; Downless;Mouse; Homolog Of; EDA-A1R; EDA1R; ED1R; ED5; Tumor necrosis factor receptorsuperfamily member EDAR. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSEYSNCGE NEYYNQTTGL CQECPPCGPG EEPYLSCGYG TKDEDYGCVPCPAEKFSKGG YQICRRHKDC EGFFRATVLT PGDMENDAEC GPCLPGYYML ENRPRNIYGM VCYSCLLAPPNTKECVGATS GASANFPGTS GSSTLSPFQH AHKELSGQGHLATALIIAMS TIFIMAIAIV LIIMFYILKT KPSAPACCTS HPGKSVEAQVSKDEEKKEAP DNVVMFSEKD EFEKLTATPA KPTKSENDAS SENEQLLSRS VDSDEEPAPD KQGSPELCLLSLVHLAREKS ATSNKSAGIQ SRRKKILDVY ANVCGVVEGL SPTELPFDCL EKTSRMLSSTYNSEKAVVKT WRHLAESFGL KRDEIGGMTD GMQLFDRIST AGYSIPELLTKLVQIERLDA VESLCADILE WAGVVPPASQ PHAAS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | EDAR protein solution (0.25mg/ml) containing 20mMTris-HCl (pH 8.0) and 10% glycerol. | ||
Ectodysplasin A Receptor, also known as EDAR belongs to the tumornecrosis factor receptor family. EDAR isa receptor for the soluble ligand ectodysplasin A, and is capable of activatingthe nuclear factor-kappaB, JNK, as well as caspase-independent cell deathpathways. EDAR is necessary for the development of hair, teeth, and otherectodermal derivatives. Furthermore, mutations in EDAR resulted in autosomaldominant and recessive forms of hypohidrotic ectodermal dysplasia.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.