EEF2K Human
目录号 : GP22484Eukaryotic Elongation Factor-2 Kinase Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Eukaryotic Elongation Factor 2 Kinase; Calcium/Calmodulin-DependentEukaryotic Elongation Factor 2 Kinase; EEF-2 Kinase; EC 2.7.11.20; EEF-2K; Calcium/Calmodulin-DependentEukaryotic Elongation Factor-2 Kinase; Calmodulin-Dependent Protein Kinase III;Eukaroytic Elongation Factor 2 Kinase; Eukaryotic Elongation Factor-2 Kinase; ElongationFactor-2 Kinase; EC 2.7.11; HSU93850; Eukaryotic elongation factor 2 kinase. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMADEDLI FRLEGVDGGQ SPRAGHDGDS DGDSDDEEGY FICPITDDPSSNQNVNSKVN KYYSNLTKSE RYSSSGSPAN SFHFKEAWKH AIQKAKHMPD PWAEFHLEDI ATERATRHRYNAVTGEWLDD EVLIKMASQP FGRGAMRECF RTKKLSNFLHAQQWKGASNY VAKRYIEPVD RDVYFEDVRL QMEAKLWGEE YNRHKPPKQVDIMQMCIIEL KDRPGKPLFH LEHYIEGKYI KYNSNSGFVR DDNIRLTPQA FSHFTFERSG HQLIVVDIQGVGDLYTDPQI HTETGTDFGD GNLGVRGMAL FFYSHACNRI CESMGLAPFD LSPRERDAVNQNTKLLQSAK TILRGTEEKC GSPRVRTLSG SRPPLLRPLS ENSGDENMSDVTFDSLPSSP SSATPHSQKL DHLHWPVFSD LDNMASRDHD HLDNHRESEN SGDSGYPSEK RGELDDPEPREHGHSYSNRK YESDEDSLGS SGRVCVEKWN LLNSSRLHLP RASAVALEVQ RLNALDLEKKIGKSILGKVH LAMVRYHEGG RFCEKGEEWD QESAVFHLEH AANLGELEAIVGLGLMYSQL PHHILADVSL KETEENKTKG FDYLLKAAEA GDRQSMILVA RAFDSGQNLS PDRCQDWLEALHWYNTALEM TDCDEGGEYD GMQDEPRYMM LAREAEMLFT GGYGLEKDPQ RSGDLYTQAAEAAMEAMKGR LANQYYQKAE EAWAQMEE. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | EEF2K protein solution (0.25 mg/ml) containing Phosphatebuffered saline (pH7.4) and 10% glycerol. | ||
Eukaryotic elongation factor-2 kinase (EEF2K) is threonine kinase whichregulates protein synthesis by means of controlling the rate of peptide chainelongation. Upon activation through a diversity of upstream kinases includingAMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a sole site,renders it unable to bind ribosomes and therefore inactive. In turn, the rate ofprotein synthesis is being reduced.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.