Eicosapentaenoyl PAF C-16
(Synonyms: 1-O-hexadecyl-2-Eicosapenaenoyl-sn-glycero-3-phosphocholine, 1-O-hexadecyl-2-Eicosapenaenoyl-sn-glyceryl-phosphocholine, 1-O-hexadecyl-2-O-Eicosapenaenoyl-sn-glyceryl-PC, PC(O-16:0/20:5)) 目录号 : GC11000A PAF analog that contains EPA
Cas No.:132196-28-2
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Eicosapentaenoyl PAF C-16 can be formed by incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, as has been demonstrated using neutrophils from monkeys and humans fed a diet enriched in fish oils. Eicosapentaenoyl PAF C-16 can serve as a substrate for PAF C-16 formation by the remodeling pathway.
Cas No. | 132196-28-2 | SDF | |
别名 | 1-O-hexadecyl-2-Eicosapenaenoyl-sn-glycero-3-phosphocholine, 1-O-hexadecyl-2-Eicosapenaenoyl-sn-glyceryl-phosphocholine, 1-O-hexadecyl-2-O-Eicosapenaenoyl-sn-glyceryl-PC, PC(O-16:0/20:5) | ||
Canonical SMILES | CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCCCCCCCCCC)=O | ||
分子式 | C44H80NO7P | 分子量 | 766.1 |
溶解度 | acidic PBS: <50 µ g/ml (from Docosahexaenoy,basic PBS: <50 µ g/ml (from Docosahexaenoy,DMF: >14.3 mg/ml (from Docosahexaen,DMSO: 1 mg/ml,Ethanol: >1.7 mg/ml (from Docosahexaeno,PBS pH 7.2: <50 µ g/ml (from Docosahexaenoy | 储存条件 | Store at -20°C |
General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。 为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。 |
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Shipping Condition | 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。 |
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 1.3053 mL | 6.5266 mL | 13.0531 mL |
5 mM | 0.2611 mL | 1.3053 mL | 2.6106 mL |
10 mM | 0.1305 mL | 0.6527 mL | 1.3053 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。