EIF3I Human
目录号 : GP23382Eukaryotic Translation Initiation Factor 3I Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Eukaryotic Translation Initiation Factor 3; Subunit I; EIF3S2;Eukaryotic Translation Initiation Factor 3; Subunit 2 Beta; 36kDa; EukaryoticTranslation Initiation Factor 3 Subunit 2; TRIP-1; eIF-3-beta; EIF3 P36; TGF-BetaReceptor-Interacting Protein 1; PRO2242; eIF3-beta; eIF3-p36; EukaryoticTranslation Initiation Factor 3 Subunit I; Eukaryotic Translation InitiationFactor 3; Subunit 2 (Beta; 36kD); Predicted Protein Of HQ2242; TGFbetaReceptor-Interacting Protein 1; eIF3i. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMKPILLQ GHERSITQIK YNREGDLLFT VAKDPIVNVW YSVNGERLGTYMGHTGAVWC VDADWDTKHV LTGSADNSCR LWDCETGKQL ALLKTNSAVR TCGFDFGGNI IMFSTDKQMGYQCFVSFFDL RDPSQIDNNE PYMKIPCNDS KITSAVWGPL GECIIAGHES GELNQYSAKS GEVLVNVKEH SRQINDIQLS RDMTMFVTASKDNTAKLFDS TTLEHQKTFR TERPVNSAAL SPNYDHVVLG GGQEAMDVTT TSTRIGKFEA RFFHLAFEEEFGRVKGHFGP INSVAFHPDG KSYSSGGEDG YVRIHYFDPQ YFEFEFEA | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | APOBEC4 protein solution (1mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol. | ||
Eukaryotictranslation initiation factor 3, subunit I (EIF3I) is part of the eukaryotictranslation initiation factor 3 (eIF-3) complex, which is essential fornumerous steps in the initiation of protein synthesis. The eIF-3 complex linkswith the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43SPIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanningof the mRNA for AUG recognition. The eIF-3 complex is also essential fordisassembly and recycling of post-termination ribosomal complexes andsubsequently prevents premature joining of the 40S and 60S ribosomal subunitsprior to initiation. Among the diseases associated with EIF3I are clonorchiasis,and tonsillitis.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.