Elcatonin
目录号 : GP21242Elcatonin
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 93.3% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Amino Acid Sequence | Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2. | ||
| Solubility | It is recommended to reconstitute the lyophilized Elcatonin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Elcatonin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Elcatonin should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Biological Activity | Biological Activity (based on net peptide) was found to be 6695.2 IU/mg. | ||
| Formulation | The protein was lyophilized with no additives. | ||
Elcatonin is a Calcitonin derivative which is transformed from eel?s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Biological Activity (based on net peptide) was found to be 6695.2 IU/mg.
Lyophilized Elcatonin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Elcatonin should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.