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Eleutheroside E Sale

(Synonyms: 刺五加苷E) 目录号 : GN10300

A glycoside with diverse biological activities

Eleutheroside E Chemical Structure

Cas No.:39432-56-9

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥1,103.00
现货
20mg
¥1,838.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Eleutheroside E, a principal component of Eleutherococcus enticosus, has anti-inflammatory and protective effects in ischemia heart. IC50 value:Target:In vitro: Treatment of 10 μM Eleutheroside E (EE) for 24 h increased basal glucose uptake as well as improved TNF-α-mediated suppression of glucose uptake. [2]In vivo: To investigate the effect of Eleutheroside E (EE) on arthritis, the CIA model in DBA/1 mice was used. Compared to vehicle-treated CIA mice, 15 mg/kg TG treatment and 30 and 60 mg/kg EE treatment obviously decreased the arthritis scores and body weight loss in CIA mice (P<0.01) [1].

References:
[1]. Chunyan He, et al. Eleutheroside E Ameliorates Arthritis Severityin Collagen-Induced Arthritis Mice Modelby Suppressing Inflammatory Cytokine Release. Inflammation, Vol. 37, No. 5, October 2014 (# 2014)
[2]. Jiyun Ahn, et al. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice. Evid Based Complement Alternat Med. 2013; 2013: 934183.

Chemical Properties

Cas No. 39432-56-9 SDF
别名 刺五加苷E
化学名 (2R,3S,4R,5R,6S)-2-[4-[6-[3,5-dimethoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Canonical SMILES COC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)O)OC)C3C4COC(C4CO3)C5=CC(=C(C(=C5)OC)OC6C(C(C(C(O6)CO)O)O)O)OC
分子式 C34H46O18 分子量 742.72
溶解度 ≥ 26.2mg/mL in DMSO 储存条件 Store at 2-8°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.3464 mL 6.732 mL 13.464 mL
5 mM 0.2693 mL 1.3464 mL 2.6928 mL
10 mM 0.1346 mL 0.6732 mL 1.3464 mL
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