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Endosulfan sulfate Sale

(Synonyms: 硫丹硫酸酯) 目录号 : GC47290

A major metabolite of the insecticide endosulfan

Endosulfan sulfate Chemical Structure

Cas No.:1031-07-8

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50 mg
¥582.00
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100 mg
¥1,113.00
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Sample solution is provided at 25 µL, 10mM.

Description

Endosulfan sulfate is a major metabolite of endosulfan, a broad-spectrum organochlorine insecticide.1 Endosulfan sulfate is formed through oxidation of endosulfan by bacteria and fungi in the environment, where it is considered a persistent organic pollutant (POP). It accumulates in the liver and gonads of wild silverside fish (O. bonariensis) and is found in higher amounts in mature fish than pre-spawning fish.2 Levels of endosulfan sulfate in the gills of mature O. bonariensis correlate with increased levels of lipid peroxidation. It is toxic to freshwater fish, including G. affinis, H. formosa, P. latipinna, and P. promelas, with LC50 values ranging from 2.1 to 3.5 µg/L after a 96-hour exposure.3 Endosulfan sulfate is the main metabolite found in the liver of mice following endosulfan administration at doses of 0.3 and 3 mg/kg.4 It decreases the levels of glutathione (GSH) and malondialdehyde (MDA), a product of lipid peroxidation, in the liver, but increases MDA in the kidney when administered at a dose of 3 mg/kg.

1.Kataoka, R., and Takagi, K.Biodegradability and biodegradation pathways of endosulfan and endosulfan sulfateAppl. Microbiol. Biotechnol.97(8)3285-3292(2013) 2.Barni, M.F.Assessment of persistent organic pollutants accumulation and lipid peroxidation in two reproductive stages of wild silverside (Odontesthes bonariensis)Ecotoxicol. Environ. Saf.9945-53(2014) 3.Carriger, J.F., Hoang, T.C., Rand, G.M., et al.Acute toxicity and effects analysis of endosulfan sulfate to freshwater fish speciesArch. Environ. Contam. Toxicol.60(2)281-289(2011) 4.Yan, J., Wang, D., Miao, J., et al.Discrepant effects of α-endosulfan, β-endosulfan, and endosulfan sulfate on oxidative stress and energy metabolism in the livers and kidneys of miceChemosphere205223-233(2018)

化学性质

Cas No. 1031-07-8 SDF
别名 硫丹硫酸酯
Canonical SMILES ClC1(C2(Cl)Cl)C(COS(OC3)(=O)=O)C3C2(Cl)C(Cl)=C1Cl
分子式 C9H6Cl6O4S 分子量 422.9
溶解度 DMSO: Slightly Soluble,Methanol: Slightly Soluble 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.3646 mL 11.8231 mL 23.6463 mL
5 mM 0.4729 mL 2.3646 mL 4.7293 mL
10 mM 0.2365 mL 1.1823 mL 2.3646 mL
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