EPHB2 Human
目录号 : GP23408EPH Receptor B2 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | EPHB2; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5; Developmentally-regulatedEph-related tyrosine kinase; ELK-related tyrosine kinase; EPH tyrosine kinase3; EPH-like kinase 5; hEK5; Renal carcinoma antigen NY-REN-47; Tyrosine-proteinkinase TYRO5; Tyrosine-protein kinase receptor EPH-3. | ||
| Amino Acid Sequence | VEETLMDSTT ATAELGWMVH PPSGWEEVSG YDENMNTIRT YQVCNVFESSQNNWLRTKFI RRRGAHRIHV EMKFSVRDCS SIPSVPGSCK ETFNLYYYEA DFDSATKTFP NWMENPWVKVDTIAADESFS QVDLGGRVMK INTEVRSFGP VSRSGFYLAF QDYGGCMSLI AVRVFYRKCP RIIQNGAIFQETLSGAESTS LVAARGSCIA NAEEVDVPIK LYCNGDGEWL VPIGRCMCKA GFEAVENGTV CRGCPSGTFKANQGDEACTH CPINSRTTSE GATNCVCRNG YYRADLDPLD MPCTTIPSAP QAVISSVNET SLMLEWTPPRDSGGREDLVY NIICKSCGSG RGACTRCGDN VQYAPRQLGL TEPRIYISDL LAHTQYTFEI QAVNGVTDQSPFSPQFASVN ITTNQAAPSA VSIMHQVSRT VDSITLSWSQ PDQPNGVILD YELQYYEKEL SEYNATAIKSPTNTVTVQGL KAGAIYVFQV RARTVAGYGR YSGKMYFQTM TEAEYQTSIQ EKLPLLEHHH HHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | EPHB2 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4), 1mM DTT and 20% glycerol. | ||
EPHReceptor B2 (EPHB2) is a part of the transmembrane Eph receptor tyrosine kinasefamily (RTKs) which binds proteins of the Ephrin family on adjacent cells. Theinteraction leads to contact-dependent bidirectional signaling into neighboringcells. Hippocampal neurons can release vesicles containing full lengthEPHB2, and these are taken up by neighboring glial cells. EPHB2 takes part inthe guidance of commissural axons through the embryonic midline and regulatesdendritic spines development and maturation and stimulates the formation ofexcitatory synapses.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.