FAS Human, His
目录号 : GP20201sFas Receptor Human Recombinant, His Tag
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile liquid formulation. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | CD95; CD-95; Tumor necrosis factor receptor superfamily member 6; FASLG receptor; Apoptosis-mediating surface antigen FAS; Apo-1 antigen; CD95 antigen; FAS; APT1; FAS1; TNFRSF6; APO-1; FASTM; ALPS1A. | ||
| Stability | CD95 although stable at 10°C for 5 days, should be stored below -18°C .Please prevent freeze-thaw cycles. | ||
| Formulation | 10mM Sodium Phosphate, pH 8.0. | ||
FAS / CD95 is a 36kDa transmembrane type I receptor, which belongs to the NF/NGF receptor super-family. It is a potent inducer of apoptosis in cells of the immune system upon interaction with its natural ligand, CD95L. Although the CD95/CD95L system could play a role in tumor regression, tumor cells seem to down-regulate CD95 expression as a mechanism of resistance to CD95L-induced killing by T lymphocytes and NK cells. The Fas antigen is expressed on the surface of various cell types, including activated T and B lymphocytes and T lymphoblastoid cell line. CD95 is also expressed in a broad panel of non-transformed cells outside the immune system.
CD95 although stable at 10°C for 5 days, should be stored below -18°C .Please prevent freeze-thaw cycles.