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Fenbendazole-d3 Sale

(Synonyms: 芬苯达唑 d3) 目录号 : GC47334

An internal standard for the quantification of fenbendazole

Fenbendazole-d3 Chemical Structure

Cas No.:1228182-47-5

规格 价格 库存 购买数量
1 mg
¥714.00
现货
5 mg
¥1,428.00
现货
10 mg
¥2,345.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Fenbendazole-d3 is intended for use as an internal standard for the quantification of fenbendazole by GC- or LC-MS. Fenbendazole is a benzimidazole anthelmintic.1 It is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection.2 It also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.3

1.Morgan, U.M., Reynoldson, J.A., and Thompson, R.C.A.Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitroAntimicrob. Agents Chemother.37(2)328-331(1993) 2.Suter, C., MÜller-Doblies, U.U., Hatt, J.-M., et al.Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazoleVet. Rec. 148(15)478-480(2001) 3.Aleyasin, H., Karuppagounder, S.S., Kumar, A., et al.Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulinAntioxid. Redox Signal.22(2)121-134(2015)

Chemical Properties

Cas No. 1228182-47-5 SDF
别名 芬苯达唑 d3
Canonical SMILES O=C(OC([2H])([2H])[2H])NC1=NC2=CC(SC3=CC=CC=C3)=CC=C2N1
分子式 C15H10D3N3O2S 分子量 302.4
溶解度 DMSO : 5 mg/mL (16.54 mM; ultrasonic and warming and heat to 60°C); DMSO : 5 mg/mL (16.54 mM; ultrasonic and warming and heat to 60°C) 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.3069 mL 16.5344 mL 33.0688 mL
5 mM 0.6614 mL 3.3069 mL 6.6138 mL
10 mM 0.3307 mL 1.6534 mL 3.3069 mL
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