FHL2 Human
目录号 : GP23497Four And A Half LIM Domains 2 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greaterthan 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | AAG11; DRAL; FHL-2; SLIM-3; SLIM3; Four and a half LIMdomains protein 2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; FHL2; RNA Binding Motif Protein 18; RNA-Binding Motif Protein 18; RBM18. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMTERFDC HHCNESLFGK KYILREESPY CVVCFETLFA NTCEECGKPIGCDCKDLSYK DRHWHEACFH CSQCRNSLVD KPFAAKEDQL LCTDCYSNEY SSKCQECKKT IMPGTRKMEYKGSSWHETCF ICHRCQQPIG TKSFIPKDNQ NFCVPCYEKQ HAMQCVQCKK PITTGGVTYR EQPWHKECFV CTACRKQLSG QRFTARDDFAYCLNCFCDLY AKKCAGCTNP ISGLGGTKYI SFEERQWHND CFNCKKCSLS LVGRGFLTER DDILCPDCGK DI. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | FHL2 protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0) and 10% glycerol. |
Four And A Half LIM Domains 2 (FHL2)belongs to the four-and-a-half-LIM-only protein family. Family members arecomprised of 2 highly conserved, tandemly arranged, zinc finger domains with 4highly conserved cysteines binding a zinc atom in each zinc finger. The FHL2protein is assumed to play a part in the assembly of extracellular membranes.Furthermore, FHL2 is down-regulated during transformation of normal myoblaststo rhabdomyosarcoma cells and the FHL2 functions as a link between presenilin-2and an intracellular signaling pathway.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.