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Flumequine-13C3 Sale

(Synonyms: 氟甲喹-13C3) 目录号 : GC49134

An internal standard for the quantification of flumequine

Flumequine-13C3 Chemical Structure

Cas No.:1185049-09-5

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1 mg
¥2,827.00
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5 mg
¥12,728.00
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Sample solution is provided at 25 µL, 10mM.

Description

Flumequine-13C3 is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1 It is active against S. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, and K. pneumoniae (MICs = 1-100 µg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 µg/ml).2 It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3 In vivo, flumequine (50 mg/kg) increases survival in rat models of P. vulgaris-induced urinary tract infection and P. mirabilis-induced prostatitis.1 Formulations containing flumequine have been used in the treatment of urinary tract infections in veterinary medicine.

1.Rohlfing, S.R., Gerster, J.R., and Kvam, D.C.Bioevaluation of the antibacterial flumequine for urinary tract useAntimicrob. Agents Chemother.10(1)20-24(1976) 2.Aller-MorÁn, L.M., MartÍnez-Lobo, F.J., Rubio, P., et al.Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriaeRes. Vet. Sci.10351-53(2015) 3.Smith, J.T.The mode of action of 4-quinolones and possible mechanisms of resistanceJ. Antimicrob. Chemother.18 (Suppl. D)21-29(1986)

化学性质

Cas No. 1185049-09-5 SDF
别名 氟甲喹-13C3
Canonical SMILES O=[13C]1C2=CC(F)=CC3=C2N(C(CC3)C)C=[13C]1[13C](O)=O
分子式 C11[13C]3H12FNO3 分子量 264.2
溶解度 Acetonitrile:Methanol (1:1): soluble,DMSO: soluble 储存条件 -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.785 mL 18.9251 mL 37.8501 mL
5 mM 0.757 mL 3.785 mL 7.57 mL
10 mM 0.3785 mL 1.8925 mL 3.785 mL
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