Fractalkine Rat
目录号 : GP21103Fractalkine Rat Recombinant (CX3CL1)
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 97.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | Fractalkine; CX3CL1; Neurotactin; CX3C membrane-anchored chemokine; Small inducible cytokine D1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine. | ||
| Amino Acid Sequence | QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG | ||
| Solubility | It is recommended to reconstitute the lyophilized Fractalkine in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized FractalkineRat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Fractalkine should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
| Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml, corresponding to a specific activity of 100,000-200,000units/mg. | ||
| Formulation | Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. | ||
Fractalkine soluble form is chemotactic for t-cells and monocytes, but not for neutrophils. Fractalkine membrane-bound form promotes adhesion of those leukocytes to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the cell surface. Fractalkine gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22.
Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml, corresponding to a specific activity of 100,000-200,000units/mg.
Lyophilized FractalkineRat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Fractalkine should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.