FURIN Human
目录号 : GP23519Furin Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Furin(Paired Basic Amino Acid Cleaving Enzyme); PCSK3; PACE; FUR; Paired Basic AminoAcid Residue-Cleaving Enzyme; EC 3.4.21.75; Paired Basic Amino Acid CleavingEnzyme (Furin; Membrane Associated Receptor Protein); Proprotein ConvertaseSubtilisin/Kexin Type 3; Furin; Membrane Associated Receptor Protein; DibasicProcessing Enzyme; Dibasic-Processing Enzyme; FES Upstream Region; EC 3.4.21; Furin;SPC1; Dibasic-processing enzyme; Paired basic amino acid residue-cleavingenzyme. | ||
| Amino Acid Sequence | MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDVY QEPTDPKFPQ QWYLSGVTQR DLNVKAAWAQ GYTGHGIVVSILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNARIGGVRMLDGE VTDAVEARSL GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFVWASGNGGREH DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKCTESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV SHSYGYGLLDAGAMVALAQN WTTVAPQRKC IIDILTEPKD IGKRLEVRKT VTACLGEPNH ITRLEHAQAR LTLSYNRRGDLAIHLVSPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD EDPSGEWVLE IENTSEANNY GTLTKFTLVLYGTAPEGLPV PPESSGCKTL TSSQACVVCE EGFSLHQKSC VQHCPPGFAP QVLDTHYSTE NDVETIRASVCAPCHASCAT CQGPALTDCL SCPSHASLDP VEQTCSRQSQ SSRESPPQQQ PPRLPPEVEA GQRLRAGLLPSHLPE. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | FURINprotein solution (1mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol. | ||
Furinis a member of the peptidase S8 family. Furin signifies the ubiquitousendoprotease activity within constitutive secretory pathways aswell as capable of cleavage at the RX (K/R) R consensus motif. Furin is considered to be one of the proteases responsiblefor the activation of HIV envelope glycoproteins gp160 as well as gp140 andmight take part in tumor progression. Among the diseases associated with FURINare dementia, familial british and plague.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.