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G CSF Human, PEG

目录号 : GP20321

Granulocyte-Colony Stimulating Factor Pegylated Human Recombinant

G CSF Human, PEG Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

Granulocyte Colony Stimulating Factor Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 18.8kDa. The PegylatedG-CSF is produced by attaching a 20kDa methoxypolyethylene glycol propionaldehyde (mPEG-ALD) to the N-terminal amino acid of G-CSFgiving a total molecular mass of 38.8kDa. G-CSF is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SEC-HPLC. Source Escherichia Coli.
Phycical Appearance Colorless, clear and transparent solution. Shipping Condition Shipped with Ice Packs.
Synonyms CSF-3; MGI-1G; GM-CSF beta; Pluripoietin; Filgrastim; Lenograstim; G-CSF; MGC45931; GCSF.
Stability G-CSF PEG should be stored refrigerated at 2бу to 8°C . Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided.
Biological Activity The ED50, calculated by the dose-dependent proliferation of murine NFS-60 indicator cells is less than 0.1 ng/ml, corresponding to a Specific Activity of 10,000,000IU/mg.
Formulation G-CSF is supplied in solution (0.69mg/ml) containing 10mM Acetate Buffer (pH 4.0), and 0.004% Polysorbate 80.

Introduction

GCSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for this gene. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This csf induces granulocytes.

Biological Activity

The ED50, calculated by the dose-dependent proliferation of murine NFS-60 indicator cells is less than 0.1 ng/ml, corresponding to a Specific Activity of 10,000,000IU/mg.

Stability

G-CSF PEG should be stored refrigerated at 2бу to 8°C . Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided.

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