GAD2 Human, Biotin
目录号 : GP21652Glutamate Decarboxylase 2 Human Recombinant, Biotinylated
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 80.0% as determined by SDS-PAGE. | Source | Sf9 insect cells. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Glutamate Decarboxylase 2 (Pancreatic Islets And Brain; 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 65 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65; GAD65; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain; 65kD); Glutamate Decarboxylase-2 (Pancreas); EC 4.1.1; GAD2. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | ||
| Formulation | GAD2 Human biotin protein solution is supplied in 16mM HEPES buffer pH-7.5, 250mM NaCl, 0.016mM Pyridoxal-5'-Phosphate, 0.16% Triton x-100 and 20% glycerol. | ||
Glutamate Decarboxylase 2 (GAD2) is one of several forms of glutamic acid decarboxylase, identified as a main autoantigen in insulin-dependent diabetes. The GAD2 enzyme is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for the GAD2 enzyme has been characterized in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. GAD2 gene may also have a role in the stiff man syndrome. In addition, GAD2 catalyzes the production of GABA.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.