BDNF, Human
目录号 : GC26734BDNF, also known as brain-derived neurotrophic factor and abrineurin, is a neurotrophin belonging to the NGF-beta family.
Sample solution is provided at 25 µL, 10mM.
BDNF, also known as brain-derived neurotrophic factor and abrineurin, is a neurotrophin belonging to the NGF-beta family. It is expressed highly in the brain, and moderately in the heart, lung, skeletal muscle and placenta. BDNF signals through its high affinity receptor gp145/trkB to exert neurotrophic properties. It has been shown to be involved in the survival and differentiation of both the central and peripheral nervous system. Specifically, BDNF regulates synaptic transmission, axonal growth and path-finding, as well as dendritic growth and morphology.
Purity | > 95% as analyzed by SDS-PAGE | Source | |
Phycical Appearance | Shipping Condition | ||
Synonyms | Brain-derived neurotrophic factor | ||
Apparent Molecular Weight | 12~14 kDa, on SDS-PAGE under reducing conditions. | ||
Biological Activity | Immobilized Human BDNF at 5 μg/ml (100 μl/well) can bind NGF R, Human-Biotin with a linear range of 0.06-4 μg/ml. | ||
Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | ||
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||
Formulation | Lyophilized after extensive dialysis against PBS. |
Immobilized Human BDNF at 5 μg/ml (100 μl/well) can bind NGF R, Human-Biotin with a linear range of 0.06-4 μg/ml.