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Falecalcitriol Sale

(Synonyms: 氟骨三醇) 目录号 : GC36026

Falecalcitriol(Fulstan; Hornel)是骨化三醇类似物,在体内有更高更长久的活性。

Falecalcitriol Chemical Structure

Cas No.:83805-11-2

规格 价格 库存 购买数量
1mg
¥7,366.00
现货
5mg 待询 待询
10mg 待询 待询

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Sample solution is provided at 25 µL, 10mM.

Description

Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.

[1]. Ito H, Ogata H, Yamamoto M, Takahashi K, Shishido K, Takahashi J, Taguchi S, Kinugasa E. Comparison of oral falecalcitriol and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism: a randomized, crossover trial. Clin Nephro [2]. Tokunaga M, Tamura M, Kabashima N, Serino R, Shibata T, Matsumoto M, Miyamoto T, Miyazaki M, Furuno Y, Takeuchi M, Abe H, Okazaki M, Otsuji Y. Falecalcitriol for conventional vitamin D therapy-resistant secondary hyperparathyroidism in a continuous ambul [3]. Iwao Y, Yamaguchi Y, Fujii K, Toba Y, Asada M, Nagano N, Yamamoto H, Hyoma K, Yamada S, Hirano H, Tone Y, Ohtani H, Saika Y, Fujii R. Long-term suppressive effect of falecalcitriol on parathyroid hormone secretion in secondary hyperparathyroidism in hemo [4]. Morii H. Falecalcitriol as a new therapeutic agent for secondary hyperparathyroidismClin Calcium. 2005 Jan;15(1):29-33. [5]. Ohtsuka N, Urayama K. Pharmacological action and clinical effects of falecalcitriol, a highly potent derivative of active vitamin D3.Nihon Yakurigaku Zasshi. 2002 Dec;120(6):427-36. [6]. Jean-Pierre BÉguÉ, DaniÈle Bonnet-Delpon.Recent advances (1995-2005) in fluorinated pharmaceuticals based on natural products. Journal of Fluorine Chemistry.Volume 127, Issue 8, August 2006, Pages 992-1012

化学性质

Cas No. 83805-11-2 SDF
别名 氟骨三醇
Canonical SMILES C[C@]([C@]/12[H])([C@H](CC2)[C@@H](CCCC(C(F)(F)F)(C(F)(F)F)O)C)CCCC1=C/C=C(C[C@@H](O)C[C@@H]3O)\C3=C
分子式 C27H38F6O3 分子量 524.58
溶解度 Soluble in DMSO 储存条件 Store at -20°C,unstable in solution, ready to use.
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 1.9063 mL 9.5314 mL 19.0629 mL
5 mM 0.3813 mL 1.9063 mL 3.8126 mL
10 mM 0.1906 mL 0.9531 mL 1.9063 mL
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第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
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