D-Galacturonic acid (hydrate)
(Synonyms: D-半乳糖醛酸) 目录号 : GC38324
A monosaccharide
Cas No.:91510-62-2
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
D-Galacturonic acid is a monosaccharide and the major component of pectin.1 It is formed from glucose in a multi-step process in which uridine-5'-diphosphoglucuronic acid is epimerized to UDP-galacturonic acid, from which D-galacturonic acid can be oligomerized to form pectin or metabolized to L-ascorbic acid , L-galactonic acid, galactaric acid, or D-(+)-xylose .1,2 D-Galacturonic acid (200, 400, and 800 mg/kg) increases body weight and reduces intestinal mucosal permeability in a rat model of iodoacetamide-induced functional dyspepsia.3
1.Gu, X., and Bar-Peled, M.The biosynthesis of UDP-galacturonic acid in plants. Functional cloning and characterization of Arabidopsis UDP-D-glucuronic acid 4-epimerasePlant Physiol.136(4)4256-4264(2004) 2.Loewus, F.A., and Kelly, S.The metabolism of D-galacturonic acid and its methyl ester in the detached ripening strawberryArch. Biochem. Biophys.95(3)483-493(1961) 3.Wu, Y.-Y., Zhong, Z.-S., Ye, Z.-H., et al.D-galacturonic acid ameliorates the intestinal mucosal permeability and inflammation of functional dyspepsia in ratsAnn. Palliat. Med.10(1)538-548(2021)
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 4.7136 mL | 23.5682 mL | 47.1365 mL |
| 5 mM | 0.9427 mL | 4.7136 mL | 9.4273 mL |
| 10 mM | 0.4714 mL | 2.3568 mL | 4.7136 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。