Patchouli alcohol
(Synonyms: 百秋李醇) 目录号 : GC38424
A natural antibiotic and anti-inflammatory alcohol
Cas No.:5986-55-0
Sample solution is provided at 25 µL, 10mM.
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Pogostemon (patchouli) leaves and their extracted oils are used in perfumes and in traditional medicine to relieve sunstroke, stop vomiting, and increase appetite.1 Patchouli alcohol is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions.1,2,3 Patchouli alcohol also suppresses inflammation induced by lipopolysaccharide in vivo.4 Topical application of patchouli alcohol accelerates recovery from ultraviolet irradiation-induced skin damage through antioxidant and anti-inflammatory effects.5
1.Zhang, R., Yan, P., Li, Y., et al.A pharmacokinetic study of patchouli alcohol after a single oral administration of patchouli alcohol or patchouli oil in ratsEur. J. Drug Metab. Pharmacokinet.41(4)441-448(2015) 2.Wu, H., Li, B., Wang, X., et al.Inhibitory effect and possible mechanism of action of patchouli alcohol against influenza A (H2N2) virusMolecules16(8)6489-6501(2011) 3.Yu, X.D., Xie, J.H., Wang, Y.H., et al.Selective antibacterial activity of patchouli alcohol against Helicobacter pylori based on inhibition of ureasePhytother. Res.29(1)67-72(2015) 4.Yu, J.L., Zhang, X.S., Xue, X., et al.Patchouli alcohol protects against lipopolysaccharide-induced acute lung injury in miceJ. Surg. Res.194(2)537-543(2015) 5.Feng, X.X., Yu, X.T., Li, W.J., et al.Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in miceEur. J. Pharm. Sci.63113-123(2014)
| Cas No. | 5986-55-0 | SDF | |
| 别名 | 百秋李醇 | ||
| Canonical SMILES | O[C@@]1(C2(C)C)CC[C@H](C)[C@]3([H])C[C@@]2([H])CC[C@]13C | ||
| 分子式 | C15H26O | 分子量 | 222.37 |
| 溶解度 | DMSO: 125 mg/mL (562.13 mM) | 储存条件 | Store at -20°C,protect from light |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 4.497 mL | 22.485 mL | 44.9701 mL |
| 5 mM | 0.8994 mL | 4.497 mL | 8.994 mL |
| 10 mM | 0.4497 mL | 2.2485 mL | 4.497 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet