Home>>Signaling Pathways>> Endocrinology and Hormones>>GLP-2 (1-34) (human) (trifluoroacetate salt)

GLP-2 (1-34) (human) (trifluoroacetate salt) Sale

(Synonyms: Glucagon-like Peptide 2 (1-34)) 目录号 : GC45463

A synthetic form of the peptide GLP-2

GLP-2 (1-34) (human) (trifluoroacetate salt) Chemical Structure

规格 价格 库存 购买数量
1mg
¥4,779.00
现货

电话:400-920-5774 Email: sales@glpbio.cn

Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

Description

GLP-2 (1-34) (human) is a synthetic form of the human peptide GLP-2 that contains the full human sequence with the addition of an arginine residue at the C-terminal end.1 It increases survival of myenteric neurons cultured alone (EC50 = 0.35 nM) and when co-cultured with mast cells to induce cell death.2 It does not stimulate insulin release from isolated rat pancreatic islets in the presence of glucose when used at concentrations ranging from 2.5 to 250 nM.1 GLP-2 (1-34) (human) also does not affect formation of adenomas in a transgenic model of intestinal tumorigenesis using ApcMin/+ mice.3

References
1. Schmidt, W.E., Siegel, E.G., and Creutzfeldt, W. Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets. Diabetologia 28(9), 704-707 (1985).
2. Voss, U., Sand, E., Hellstr•m, P.M., et al. Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons. BMC Gastroenterol. 12, 30 (2012).
3. Koehler, J.A., Harper, W., Barnard, M., et al. Glucagon-like peptide-2 does not modify the growth or survival of murine or human intestinal tumor cells. Cancer Res. 68(19), 7897-7904 (2008).

化学性质

Cas No. SDF
别名 Glucagon-like Peptide 2 (1-34)
Canonical SMILES OCC1=C(O)C=CC(C(O)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C1
分子式 C171H266N48O56S.XCF3COOH 分子量 3922.3
溶解度 Water: 1 mg/ml 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 0.255 mL 1.2748 mL 2.5495 mL
5 mM 0.051 mL 0.255 mL 0.5099 mL
10 mM 0.0255 mL 0.1275 mL 0.255 mL
  • 摩尔浓度计算器

  • 稀释计算器

  • 分子量计算器

质量
=
浓度
x
体积
x
分子量
 
 
 
*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % saline
计算重置

产品文档

Quality Control & SDS

View current batch: