TPTZ
(Synonyms: 2,4,6-三(2-吡啶基)三嗪) 目录号 : GC45581
A colorimetric reagent for the detection of iron
Cas No.:3682-35-7
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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- Purity: >99.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
TPTZ is a colorimetric reagent commonly used in the detection of iron.1,2 TPTZ forms a complex with Fe(II) that can be quantified by colorimetric detection at 594 nm as a measure of iron concentration.
References
1. Collins, P.F., and Diehl, H. 2,4,6-Tripyridyl-s-triazine as a reagent for iron. Determination of iron in limestone, silicates, and refractories. Anal. Chem. 31(11), 1862-1867 (1959).
2. Dehghani, Z., Dadfarnia, S., Shabani, A.M.H., et al. Determination of iron species by combination of solvent assisted-dispersive solid phase extraction and spectrophotometry. Anal. Bioanal. Chem. Res. 2(1), 13-21 (2015).
| Cas No. | 3682-35-7 | SDF | |
| 别名 | 2,4,6-三(2-吡啶基)三嗪 | ||
| Canonical SMILES | C1(C2=NC(C3=NC=CC=C3)=NC(C4=CC=CC=N4)=N2)=CC=CC=N1 | ||
| 分子式 | C18H12N6 | 分子量 | 312.3 |
| 溶解度 | DMF: 10mg/mL,DMSO: 10mg/mL,Ethanol: 20mg/ml,Ethanol:PBS (pH 7.2) (1:4): 0.2mg/mL | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.202 mL | 16.0102 mL | 32.0205 mL |
| 5 mM | 0.6404 mL | 3.202 mL | 6.4041 mL |
| 10 mM | 0.3202 mL | 1.601 mL | 3.202 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
2,4,6-Tris(2-pyridyl)-1,3,5-triazine (TPTZ)-derived [Ru(II)(TPTZ)(acac)(CH3CN)]+ and mixed-valent [(acac)2Ru(III){(mu-tptz-H+)-}Ru(II)(acac)(CH3CN)]+
Inorg Chem 2006 Mar 20;45(6):2413-23.PMID:16529460DOI:10.1021/ic0514288.
Mononuclear [Ru(II)(TPTZ)(acac)(CH3CN)]ClO4 ([1]ClO4) and mixed-valent dinuclear [(acac)2Ru(III){(mu-tptz-Eta+)-}Ru(II)(acac)(CH3CN)]ClO4 ([5]ClO4; acac = acetylacetonate) complexes have been synthesized via the reactions of Ru(II)(acac)2(CH3CN)2 and 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPTZ), in 1:1 and 2:1 molar ratios, respectively. In [1]ClO4, TPTZ binds with the Ru(II) ion in a tridentate N,N,N mode (motif A), whereas in [5]ClO4, TPTZ bridges the metal ions unsymmetrically via the tridentate neutral N,N,N mode with the Ru(II) center and cyclometalated N,C- state with the Ru(III) site (motif F). The activation of the coordinated nitrile function in [1]ClO4 and [5]ClO4 in the presence of ethanol and alkylamine leads to the formation of iminoester ([2]ClO4 and [7]ClO4) and amidine ([4]ClO4) derivatives, respectively. Crystal structure analysis of [2]ClO4 reveals the formation of a beautiful eight-membered water cluster having a chair conformation. The cluster is H-bonded to the pendant pyridyl ring N of TPTZ and also with the O atom of the perchlorate ion, which, in turn, makes short (C-H- - - - -O) contacts with the neighboring molecule, leading to a H-bonding network. The redox potentials corresponding to the Ru(II) state in both the mononuclear {[(acac)(TPTZ)Ru(II)-NC-CH3]ClO4 ([1]ClO4) >> [(acac)(TPTZ)Ru(II)-NH=C(CH3)-OC2H5]ClO4 ([2]ClO4) > [(acac)(TPTZ)Ru(II)-NH2-C6H4(CH3)]ClO4 ([3]ClO4) > [(acac)(TPTZ)Ru(II)-NH=C(CH3)-NHC2H5]ClO4 ([4]ClO4)} and dinuclear {[(acac)2Ru(III){(mu-tptz-H+)-}Ru(II)(acac)(NC-CH3)]ClO4 ([5]ClO4), [(acac)2Ru(III){(mu-tptz-H+(N+-O-)2)-}Ru(II)(acac)(NC-CH3)]ClO4 ([6]ClO4), [(acac)2Ru(III){(mu-tptz-H+)-}Ru(II)(acac)(NH=C(CH3)-OC2H5)]ClO4 ([7]ClO4), and [(acac)2Ru(III){(mu-tptz-Eta+)-}Ru(II)(acac)(NC4H4N)]ClO4 ([8]ClO(4))} complexes vary systematically depending on the electronic nature of the coordinated sixth ligands. However, potentials involving the Ru(III) center in the dinuclear complexes remain more or less invariant. The mixed-valent Ru(II)Ru(III) species ([5]ClO4-[8]ClO4) exhibits high comproportionation constant (Kc) values of 1.1 x 10(12)-2 x 10(9), with substantial contribution from the donor center asymmetry at the two metal sites. Complexes display Ru(II)- and Ru(III)-based metal-to-ligand and ligand-to-metal charge-transfer transitions, respectively, in the visible region and ligand-based transitions in the UV region. In spite of reasonably high K(c) values for [5]ClO4-[8]ClO4, the expected intervalence charge-transfer transitions did not resolve in the typical near-IR region up to 2000 nm. The paramagnetic Ru(II)Ru(III) species ([5]ClO4-[8]ClO4) displays rhombic electron paramagnetic resonance (EPR) spectra at 77 K (g approximately 2.15 and Deltag approximately 0.5), typical of a low-spin Ru(III) ion in a distorted octahedral environment. The one-electron-reduced TPTZ complexes [Ru(II)(TPTZ.-)(acac)(CEta3CN)] (1) and [(acac)2Ru(III){(mu-tptz-Eta+).2-}Ru(II)(acac)(CH3CN)] (5), however, show a free-radical-type EPR signal near g = 2.0 with partial metal contribution.
Spectroscopic, analytical and DFT calculation studies of two novel Al3+ complexes derived from 2,4,6-tri-(2-pyridyl)-1,3,5-triazine (TPTZ)
Spectrochim Acta A Mol Biomol Spectrosc 2014 Nov 11;132:165-73.PMID:24858358DOI:10.1016/j.saa.2014.03.073.
In this study TPTZ is used exclusively as an analytical reagent for the determination of micro amounts of Al3+ ions with high accuracy and lower detection limit, which reach 2.7 ppm. The developed blue color of Al3+-TPTZ complex was used selectivity to determine the concentration and the geometry of the Al3+ complex using continuous variation and molar ratio methods. Also, the novel Al3+ complexes derived from the reaction of TPTZ were synthesized. The solid complexes were characterized by elemental analyses, spectral (IR, UV-vis., 1H NMR, mass) and magnetic measurements. The isolated complexes have the general formulae, [Al(TPTZ)Cl3]·H2O·1½EtOH (1:1; M:L) and [Al2(TPTZ)Cl6(EtOH)2] (2:1; M:L). IR spectra indicate that TPTZ behaves in a bidentate manner in case of 1:1 and 2:1 (M:L). Elemental analyses and mass spectra of the complexes suggest the existence of an octahedral structure around the Al3+ ions. DFT calculations were used to determine the geometry of complexes.
Dibromido(2,4,6-tri-2-pyridyl-1,3,5-triazine-κN,N,N)manganese(II)
Acta Crystallogr Sect E Struct Rep Online 2011 Dec 1;67(Pt 12):m1655.PMID:22199482DOI:10.1107/S1600536811045211.
The Mn(II) ion in the title complex, [MnBr(2)(C(18)H(12)N(6))], is five-coordinated in a distorted square-pyramidal geometry by three N atoms of the tridentate 2,4,6-tri-2-pyridyl-1,3,5-triazine (TPTZ) ligand and two bromide anions. In the crystal, the pyridyl rings coordinated to the Mn atom are inclined slightly to their carrier triazine ring [dihedral angles = 8.0 (3) and 7.5 (3)°], whereas the uncoordinated pyridyl ring is located approximately parallel to the triazine ring [dihedral angle = 3.7 (3)°]. The complexes are stacked in columns along the a axis and linked by inter-molecular C-H⋯Br hydrogen bonds, forming chains. In the column, inter-molecular π-π inter-actions between the six-membered rings are present, the shortest centroid-centroid distance being 3.750 (4) Å.
Sensitive Fluorescent Determination of Cobalt by Microwave Assisted Synthesized TPTZ Functionalized Carbon Dots
J Fluoresc 2018 Jan;28(1):251-257.PMID:29124631DOI:10.1007/s10895-017-2187-y.
Novel fluorescent carbon dots (CDs) for cobalt ions sensing were synthesized from 2,4,6-tris(2'-pyridyl)-s-triazine (TPTZ) and citric acid by microwave-assisted method in one pot. This sensor was water soluble, simple, sensitive and cheap. The size of the CDs was determined from transmission electron microscope image and was in the range of 10 nm. Under optimized experimental conditions, this luminescent system had stable response for Co (II) over a concentration range from 0.4 to 50 µM with a detection limit as low as 230 nM. The proposed method showed good sensitivity and selectivity with respect to interference ions. Finally, this system was used for Co (II) determination in tap water, river water and mineral water and B12 ampoule samples.
Lanthanide-3d cyanometalate chains Ln(III)-M(III) (Ln=Pr, Nd, Sm, Eu, Gd, Tb; M=Fe) with the tridentate ligand 2,4,6-tri(2-pyridyl)-1,3,5-triazine (TPTZ): evidence of ferromagnetic interactions for the Sm(III)-M(III) compounds (M=Fe, Cr)
Dalton Trans 2007 Feb 28;(8):878-88.PMID:17297516DOI:10.1039/b616016f.
A series of cyanide-bridged chain mixed Fe(III)/Ln(III) (Ln=Pr, Nd, Sm, Eu, Gd, Tb) complexes with the tridentate ligand 2,4,6-tri(2-pyridyl)-1,3,5-triazine (TPTZ) used as a capping group has been prepared. Reactions of TPTZ and LnCl3 with K3Fe(CN)6 yield a family of air-stable 1-D compounds {[Pr(TPTZ)(H2O)4Fe(CN)6].8H2O}infinity, {[Nd(TPTZ)(H2O)4Fe(CN)6].8H2O}infinity, {[Sm(TPTZ)(H2O)4Fe(CN)6].8H2O}, {[Eu(TPTZ)(H2O)4Fe(CN)6].6H2O}infinity, {[Gd(TPTZ)(H2O)4Fe(CN)6].6H2O}infinity, and {[Tb(TPTZ)(H2O)4Fe(CN)6].8H2O}infinity. Temperature dependent magnetic susceptibility studies of reveal that in , the Sm(III) and Fe(III) ions are ferromagnetically coupled with 3-D ordering occurring below 3.5 K. The appearance of the frequency dependent out-of-phase signal is explained in terms of an ordering with a spin glass-like behavior. To compare the magnetic behavior of with related compounds, {[Sm(TPTZ)(H2O)4Co(CN)6].8H2O}infinity and {[La(TPTZ)(DMF)(H2O)3Fe(CN)6].5H2O}infinity, {[Sm(tmphen)(DMF)3(H2O)Fe(CN)6].2H2O}infinity, {[Sm(tmphen)2(H2O)2Fe(CN)6].MeOH.13H2O}infinity and {[Sm(tmphen)2(H2O)2Cr(CN)6].MeOH.9H2O}infinity with 3,4,7,8-tetramethyl-1,10-phenanthroline (tmphen) were also prepared.