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GHBP Human, His

目录号 : GP20349

Growth Hormone Binding Protein Human Recombinant, His Tag

GHBP Human, His Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

GHBP produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 254 amino acids (19-264a.a.) and having a molecular mass of 29.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).GHBP is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 95.0% as determined by SDS-PAGE. Source Sf9,Insect cells.
Phycical Appearance Sterilefiltered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Growth Hormone Receptor; Growth Hormone Binding Protein; SomatotropinReceptor GH Receptor; Serum BindingProtein; GHBP; GHIP.
Amino Acid Sequence FSGSEATAAI LSRAPWSLQS VNPGLKTNSS KEPKFTKCRS PERETFSCHWTDEVHHGTKN LGPIQLFYTR RNTQEWTQEW KECPDYVSAG ENSCYFNSSF TSIWIPYCIK LTSNGGTVDEKCFSVDEIVQ PDPPIALNWT LLNVSLTGIH ADIQVRWEAP RNADIQKGWM VLEYELQYKEVNETKWKMMD PILTTSVPVYSLKVDKEYEV RVRSKQRNSG NYGEFSEVLY VTLPQMSQFT CEEDFYLEHH HHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation GHBP protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

Introduction

Growth hormone receptor, also known as GHR is part of the cytokinereceptor family. GHR binds 2 receptormolecules and in this manner induces signal transduction through receptordimerization. Furthermore, at high concentrations, growth hormone performs asan antagonist since there is a large difference in affinities at the respectivebinding sites. The antagonist action can be enhanced further by reducingbinding in the low affinity binding site.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.