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Ginkgolic Acid C13:0 (Ginkgolic acid (13:0)) Sale

(Synonyms: 白果新酸,Ginkgolic acid (13) 目录号 : GC33980

An anacardic acid with diverse biological activities

Ginkgolic Acid C13:0 (Ginkgolic acid (13:0)) Chemical Structure

Cas No.:20261-38-5

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1mg
¥257.00
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5mg
¥540.00
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10mg
¥945.00
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Sample solution is provided at 25 µL, 10mM.

Description

Ginkgoneolic acid is an anacardic acid and analog of anacardic acid monoene originally isolated from G. biloba and has diverse biological activities.1,2,3,4 It inhibits glycerol-3-phosphate dehydrogenase (GPDH; IC50 = 3 μg/ml).1 Ginkgoneolic acid inhibits PI3Kδ (IC50 = 2.49 μM) and IgE-mediated RBL-2H3 mast cell degranulation in vitro (IC50 = 2.4 μM).2 It reduces S. mutans biofilm formation with a 50% biofilm inhibition concentration (MBIC50) value of 4 μg/ml.3 Ginkgoneolic acid is molluscicidal against O. hupensis when used at a concentration of 2 mg/L.4

1.Irie, J., Murata, M., and Homma, S.Glycerol-3-phosphate dehydrogenase inhibitors, anacardic acids, from Ginkgo bilobaBiosci. Biotechnol. Biochem.60(2)240-243(1996) 2.Guo, J.-F., Ning, Z.-Q., Wu, X., et al.Discovery of a natural PI3Kδ inhibitor through virtual screening and biological assay studyBiochem. Biophys. Res. Commun.508(3)709-714(2019) 3.He, J., Wang, S., Wu, T., et al.Effects of ginkgoneolic acid on the growth, acidogenicity, adherence, and biofilm of Streptococcus mutans in vitroFolia Microbiol. (Praha)58(2)147-153(2013) 4.Yang, X.-m., Chen, S.-x., Xia, L., et al.Molluscicidal activity against Oncomelania hupensis of Ginkgo bilobaFitoterapia79(4)250-254(2008)

化学性质

Cas No. 20261-38-5 SDF
别名 白果新酸,Ginkgolic acid (13
Canonical SMILES O=C(O)C1=C(CCCCCCCCCCCCC)C=CC=C1O
分子式 C20H32O3 分子量 320.47
溶解度 DMF: 30 mg/ml,DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 25 mg/ml,Ethanol: 25 mg/ml 储存条件 4°C, protect from light
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.1204 mL 15.6021 mL 31.2042 mL
5 mM 0.6241 mL 3.1204 mL 6.2408 mL
10 mM 0.312 mL 1.5602 mL 3.1204 mL
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