[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate)
(Synonyms: Gly8,36,Glu22-Glucagon-like Peptide 1 (7-37)) 目录号 : GC91861[Gly8,36,Glu22]-Glucagon-like peptide 1 ([Gly8,36,Glu22]-GLP-1) (7-37) is a derivative of GLP-1 containing alanine-to-glycine, glycine-to-glutamate, and arginine-to-glycine substitutions at positions 8, 22, and 36, respectively, and a peptide fragment of the GLP-1 receptor (GLP-1R) agonist dulaglutide.
![[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate) Chemical Structure](/media/struct/GC9/GC91861.png "[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate) Chemical Structure")
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
[Gly8,36,Glu22]-Glucagon-like peptide 1 ([Gly8,36,Glu22]-GLP-1) (7-37) is a derivative of GLP-1 containing alanine-to-glycine, glycine-to-glutamate, and arginine-to-glycine substitutions at positions 8, 22, and 36, respectively, and a peptide fragment of the GLP-1 receptor (GLP-1R) agonist dulaglutide.[1]
References:
[1].Glaesner, W., Vick, A.M., Millican, R., et al.Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion proteinDiabetes Metab. Res. Rev.26(4)287-296(2010).
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 0.3017 mL | 1.5085 mL | 3.017 mL |
| 5 mM | 0.0603 mL | 0.3017 mL | 0.6034 mL |
| 10 mM | 0.0302 mL | 0.1508 mL | 0.3017 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。