GMCSF Porcine
目录号 : GP20362粒细胞巨噬细胞集落刺激因子重组猪
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | CSF-2; MGI-1GM; GM-CSF; Pluripoietin-alpha; Molgramostin; Sargramostim. | ||
| Amino Acid Sequence | MAPTRPPSPV TRPWQHVDAI KEALSLLNNS NDTAAVMNET VDVVCEMFDP QEPTCVQTRL NLYKQGLRGS LTRLKSPLTL LAKHYEQHCP LTEETSCETQ SITFKSFKDS LNKFLFTIPF DCWGPVKK. | ||
| Solubility | It is recommended to reconstitute the lyophilized GMCSF in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized GMCSF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution GMCSF should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50, as determined by TF-1 cell proliferation is <10ng/ml corresponding to a specific activity which is ≥ 1.0 x 10^5 units/mg. | ||
| Formulation | The protein was lyophilized from a sterile (0.2µm) filtered solution containing 10mM sodium phosphate, pH 7.5. | ||
GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of GMCSF is found extracellularly as a homodimer. GMCSF has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
The ED50, as determined by TF-1 cell proliferation is <10ng/ml corresponding to a specific activity which is ≥ 1.0 x 10^5 units/mg.
Lyophilized GMCSF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution GMCSF should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.