GMFB Mouse
目录号 : GP20365Glia Maturation Factor Beta Mouse Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | Glia maturation factor beta; GMFB; GMF-B; GMF-beta; GMF; C79176; AI851627; D14Ertd630e; 3110001H22Rik; 3110001O16Rik. | ||
Amino Acid Sequence | SESLVVCDVA EDLVEKLRKF RFRKETHNAA IIMKIDKDER LVVLDEELEGVSPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQMMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H. | ||
Solubility | It is recommended to reconstitute the lyophilized GMFB in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
Stability | Lyophilized GMF-B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution GMF-beta should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
Formulation | The GMF-beta protein was lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. |
GMFB is part of the GMF subfamily of the larger actin-binding protein ADF family. GMFB is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
Lyophilized GMF-B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution GMF-beta should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.