Goserelin
目录号 : GP21262Goserelin (ICI 118630) 是促性腺激素释放激素 (GnRH/LHRH) 的十肽类似物，可作为 GnRH 激动剂发挥作用。
Sample solution is provided at 25 µL, 10mM.
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Goserelin contains 10 amino acids Glu1-His2-Trp3-Ser4-Tyr5-D-Ser(tBu)6-Leu7-Arg8-Pro9-AzGly10-NH2 and having a molecular weight of 1269.43 Dalton.
| Purity | Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Store at 2-8°C |
| Solubility | It is recommended to reconstitute the lyophilized Goserelin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Goserelin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Goserelin should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Formulation | The Goserelin peptide was lyophilized with no additives. | ||
Goserelin is a hormone similar to the one normally released from the hypothalamus gland in the brain (GnRH super-agonist). It is used to treat for prostate and breast cancer.Goserelin decreases the amount of estrogen and testosterone by this treating endometriosis and cancer of the breast, and can help thin the uterus lining before surgery. Goserelin prevents the growth of tissue associated with endometriosis.Reducing the amount of testosterone is one way of treating prostate cancer.
Lyophilized Goserelin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Goserelin should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.