IL-1β, Rat
目录号 : GP29025
Sample solution is provided at 25 µL, 10mM.
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| Purity | >95% as analyzed by SDS-PAGE; >95% as analyzed by HPLC | Source | Escherichia Coli. |
| Phycical Appearance | Shipping Condition | ||
| Synonyms | IL1B; IL-1; IL1-BETA; IL1F2; interleukin 1 beta; IL1beta | ||
| Solubility | It is recommended to reconstitute the lyophilized Interleukin 1b in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Upon receiving, this product remains stable for up to 6 months at ower than -70°C. Upon reconstitution, the product should be stablefor up to 1 week at 4°C or up to 3 months at -20°C. For long term storae it is recommended that a carrier protein (example 0.1% BSA)be added. Avoid repeated freezethaw cycles. | ||
| Biological Activity | ED50 < 10.0 pg/ml, measured by a cell proliferation assay using mouse D10S cells, corresponding to a specific activity of > 1.0 x 108 units/mg. | ||
| Formulation | Lyophilized after extensive dialysis against PBS. | ||
Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin from synovial cells.
ED50 < 10.0 pg/ml, measured by a cell proliferation assay using mouse D10S cells, corresponding to a specific activity of > 1.0 x 108 units/mg.
Upon receiving, this product remains stable for up to 6 months at ower than -70°C. Upon reconstitution, the product should be stablefor up to 1 week at 4°C or up to 3 months at -20°C. For long term storae it is recommended that a carrier protein (example 0.1% BSA)be added. Avoid repeated freezethaw cycles.