GZMH Human, sf9
目录号 : GP21768Granzyme-H Human Recombinant, sf9
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 90.0% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Granzyme H; Granzyme H (Cathepsin G-Like 2; ProteinH-CCPX); Cytotoxic T-Lymphocyte Proteinase; Cathepsin G-Like 2; CTSGL2; CCP-X;CSP-C; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Cathepsin G-Like 2;Protein H-CCPX; Cytotoxin Serine Protease-C; Cytotoxic Serine Protease C;Protein H-CCPX; EC 3.4.21.79; EC 3.4.21; EC 3.4.21; CTLA1; CGL-2 ; CGL2. | ||
| Amino Acid Sequence | EEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGSSINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKPGQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVCKDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRLHH HHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | GZMH protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
Granzyme H also known as GZMH belongs to the peptidase S1 family. GZMH is an essential part for HBV eradication. The HBx protein, which is required for the replication of HBV, is cleaved at Met(79) by GZMH. Furthermore, GZMH inhibitor can abolish GZNH- as well as lymphokine-activated killer cell-mediated HBx degradation and HBV clearance. A HBx-deficient HBV is resistant to GzmH- in addition to lymphokine-activated killer cell-mediated viral clearance.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.