H2AFZ Human
目录号 : GP23609H2A Histone Family, Member Z Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | H2A Histone Family; Member Z; H2AZ; H2A/z; H2A.Z-1; H2A.z;H2AZ Histone; Histone H2A.Z. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAGGKAG KDSGKAKTKA VSRSQRAGLQ FPVGRIHRHL KSRTTSHGRVGATAAVYSAA ILEYLTAEVL ELAGNASKDL KVKRITPRHL QLAIRGDEEL DSLIKATIAG GGVIPHIHKSLIGKKGQQKT V | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | H2AFZ protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. | ||
HistoneH2A.Z (H2AFZ) belongs to the histone H2A family. Histones are basic nuclearproteins which are responsible for the nucleosome structure of the chromosomalfiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrappedaround a histone octamer composed of pairs of each of the four core histones(H2A, H2B, H3, and H4). H2AFZ is implicated in the formation of constitutiveheterochromatin and vital for chromosome segregation during cell division.Moreover, variant Histone H2A, which takes the place of conventional H2A in asubset of nucleosomes. Studies in mice have demonstrated that this particularhistone is essential for embryonic development and show that lack of functionalhistone H2A leads to embryonic lethality.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.