HARS Human
目录号 : GP21775Histidyl-tRNA Synthetase Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 95.0% as determined by Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Histidyl-tRNA synthetase; EC 6.1.1.21; Histidine-tRNA ligase; HisRS; HRS; FLJ20491; JO-1; HARS. | ||
| Stability | Histidyl-tRNA Synthetase although stable at 4°C for 3 weeks, should be stored below -18°C .Please prevent freeze-thaw cycles. | ||
| Formulation | The protein solution contains 500mM NaCl and 10mM Tris (pH 8.0) and 6M Urea. | ||
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Western Blot: Strongly reactive with human anti Histidyl-tRNA Synthetase antisera.
Histidyl-tRNA Synthetase although stable at 4°C for 3 weeks, should be stored below -18°C .Please prevent freeze-thaw cycles.