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HBV core delta

目录号 : GP25329

Hepatitis B Virus Core delta Recombinant

HBV core delta Chemical Structure

规格 价格 库存 购买数量
100μg
¥2,310.00
5-10工作日
500μg
¥9,240.00
5-10工作日
1mg
¥18,900.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

The E.coli derived 14kDa recombinant protein contains the HBV core delta ayw immunodominant region amino acids 1-144.

Product Data

Purity HBV Core Delta protein is >95% pure as determined bySDS-PAGE (coomassie staining). Source
Phycical Appearance Shipping Condition Shipped with Ice Packs.
Stability HBV Core Delta protein although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.
Formulation 7.5mM Phosphate buffer pH-7.2, 75mM NaCl, & 50% glycerol.

Introduction

Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.

Purification Method

Purified by proprietary chromatographic technique.

Applications

HBV Core Delta antigen is suitable for ELISA and Western blots, excellent antigen for detection of HBV with minimal specificity problems.

Stability

HBV Core Delta protein although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.

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